I came across David Sinclair and his research into reverse aging. Especially, I came across this video by Veritasium with Sinclair. Apparently his team has managed to reverse aging in mice in a lab? Has this been peer reviewed?
I personally want to believe Sinclair, but he just… seems snake oil salesman-ey for some reason. For one, the channels that he seems to come on are the same channels that host manosphere/pseudoscience/conspiracy related guests. Secondly, he talks a lot of shit about his fellow scientists and just seems a little egoistic? I dunno…
Also, the recommendations that he seems to give (like reducing protein intake) to slow aging just seem to be against conventional wisdom? Also, for the drugs that he recommends taking, wouldn’t the FDA approve them if they actually worked? I dunno. This isn’t how a man of science behaves, right?
Anyway, aside from Sinclair, how far have we gotten in the reverse aging/stopping aging or whatever science? Should we hope to get drugs/treatment to cure this in the next 10/30/50 years?
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Sinclair is ok. He wrote a book called “lifespan” that’s pretty well regarded. Also look up Aubrey de Grey. His book, Ending Aging, is also good. He himself is problematic though. If you’re interested in this sort of tech, also look up the SENS foundation (I donate there).
Fair warning, most everything focuses on increasing healthspan, not lifespan. I.e. Being able to be active and alert at 90. There’s no way for tech to guarantee an increase in lifespan within our lives, because we would need a few generations of evidence to guarantee that. So at most you’ll get partial evidence and animal models. But you gotta start somewhere. And if we’re lucky, we’ll stop be around for the ‘proof’ in 200 years :-)
I would trust your instincts on this guy.
Science has known for years that the fewer calories you ingest, the slower you age. Metabolic processes induce a lot of wear and tear.
As far as reversing aging, the protein thing may have some merit, but I would remain skeptical for now. My 2-cent guess is that truly reversing aging will involve some unholy cocktail recipe of stem cells, genetic manipulation using CRISPR, lots of fasting, and maybe some advanced vaccines (we’re learning vaccines can train the immune system to do all sorts of interesting things beyond fighting infections).
