I’d never realized how convenient/natural a joystick is for adjusting your side mirrors. I’m not even sure my wife has the reach to both press a touchscreen in the center console and have her head in driving position to adjust the mirrors with real time feedback. Even I’d hate to have to tweak a mirror while driving with a touchscreen.

The implication is that it’s your own blood, but I like the planning/forethought. I think you’ll be going places. Probably at a run.

Feel the hate. Let it flow through you.

Indeed, I’m not sure even testing is sufficient. My family recently got it (my wife and I visiting my parents), but thought nothing of it for a week. My father had a sore throat, my mother had watery eyes and some nasal congestion. My father masked indoors (because I don’t want a regular cold either) and chalked my mother’s symptoms to seasonal allergies (the cars were covered with Pine pollen all week). Then, on the drive home, my wife felt off. 10 hours in the car together. She slept in the guest room that night and, just for grins, tested for Covid the next morning. She was positive. We called and had my parent’s test - both positive. I tested negative so I packed my things and rented a hotel room for the week and worked there alone. I tested every other day and was never positive, but I cancelled all my client meetings.

I still never “got it” but…is it really feasible I didn’t have some low level? This is my second trip in a car for multiple hours with someone who tested positive the next day. Granted, I’m about 4 vaccines in (2xOG, 1 updated, 1 XBB variant), but so is my wife. I have to think that I had some sub-clinical level of viral load, or at least below the antigen test threshold, but I’m thankful I escaped symptoms.

Not to defend them or minimize the corporate stupidity, but it sounded like there were less than 100k people affected out of tens of millions (100m?) accounts. I get that it was a big deal for those affected, but a 0.1% outage doesn’t seem “major”.

deleted by creator

Still cheaper than inkjets

The description of an unexpected/(impossible) orientation for an on road obstacle works as an excuse, right up to the point where you realize that the software should, explicitly, not run into anything at all. That’s got to be, like, the first law of (robotic) vehicle piloting.

It was just lucky that it happened twice as, otherwise, Alphabet likely would have shrugged it off as some unimportant, random event.

11. When you die at the palace, you really die at the palace
12. Try the mulled wine
13. It’s good to be the king
14. A gentleman’s cuffs should be even with the tip of his penis
15. Jews can joke about whatever they want if they’re the scriptwriter

Doubtful. 20 years in Afghanistan bought us nothing. Half a century of meddling in the rest of central America has produced refugee waves. While we could, theoretically, try to assist the Mexican government with funds we’d probably fuck that up too.

Any braking without energy recovery is wildly wasteful. Public transit (busses, trains) are fucking terrible wastes of energy due to their large mass and frequent stops. Hybrid and/or electric busses are, in this respect, potentially far superior to their diesel counterparts. I’m not a train person (engineer…train…haha) but I don’t think even the all electric trains use regenerative braking and there are few battery powered trains in service.

I’ve spent the last year altering my driving habits when I can. I try not to be an asshole when others are around/in traffic, but when I’m not pressed I will coast to a stop as much as possible (esp uphill) and use hills to gain momentum. Over 6000 miles, I’ve raised my overall mpg around 18%.

Not quite. EVs can still do door to door transport, are faster portal to portal, and have a vastly more diverse infrastructure, including the ability to (at least in a limited extent) traverse areas without track or road infrastructure. Public transit is still better, especially for rail, in reducing energy losses due to wheel deformation, reduction of human fatigue and dependence on attentiveness, and in some cases station to station speed and net air resistance per passenger mile. Since this is technology instead of fuckcars, it seems reasonable not to circlejerk too much.

In traffic, the largest reduction of efficiency comes from accelerating and the braking. You use energy to start moving (proportional to m V^2) and then you dump that energy into heat in your brakes to stop. The second comes from idling where you use energy to keep the engine rotating. As others have mentioned, EVs use regenerative braking so a substantial portion of the energy used to slow and stop the car is used to recharge the battery. EVs have no need to keep an engine running so unless you’re running the a/c there are minimal demands on a stopped/idling EV.

On the highway, you have the internal friction in the drivetrain to overcome, the constant deformation of the tires, and - most importantly - wind resistance, which is proportional to cd x rho x V2.

Cd (drag) and rho (air density) are low, but that V (speed) squared means driving at 75mph incurs 25x the energy use as driving at 15 mph. An EV gets no sage harbor here - plowing through a fluid (air) is essentially the same work.

To give you a sense of numbers, my vehicle (F150) gets less than 10mpg the 5 miles to my local pool/gym. The speed limit is 25 mph but there are stop signs every block or two. Lots of braking loss. On back roads with gentle curves and a 45 mph limit I get close to 30 mpg. That’s the sweet spot between overcoming transmission friction and air resistance. On the highway at 60 mph I get 22-23 mpg. At 78-79 mph I get 19 mpg. These are all generally on flat stretches using the 6 min average on my dashboard.

(Sorry for the long post…I’m an engineer and mechanical efficiency and aerodynamics are my happy place)

ICU docs who deal with many flu, COVID and other respiratory critical illness

While almost certainly not incompetent at their jobs, they have little reason to have specific knowledge of vaccine efficacy. Without some active immunological research component (which an ICU doctor is unlikely to undertake), they are practitioners seeing a self-selecting population and drawing conclusions from anecdotal evidence. You may as well ask an auto mechanic what they think of a newly formulated fuel additive. Not a slight to the doctors, but a recognition that it’s not their specialty no matter how many vehicles they see.

I’ve read the same thing - that the current iteration of the vaccine is not specific to the most prevalent version of Covid at the moment and is not exceptionally effective at preventing infection. But I’ve also read that the prevalence of complications from the most recent strain are substantially decreased for those who have gotten (the|a recent) vaccine booster. I wouldn’t trust me or my knowledge either though, as I’m not a doctor, much less a degree in immunology. For my information I usually get updates from a good friend who has her PhD in immunology, worked in a lab for two decades, and is now a scientific writer for an immunological journal and sees many of the new research papers coming out.

Personally, it costs me nothing financially to get the vaccine and my reaction is minor at worst with no down time. Same as influenza. OTOH, I stand to lose a great deal, financially, if I get sick (no work=no income) so I will continue to get boosted as new versions come out and I’m eligible.

In many cases,in the US, the rack rate for a full course of a serious cancer is easily the $500k I suggested and frequently more than double that. My treatment for a suspected single point melanoma was close to $75,000 and it was a single outpatient procedure with a pre- and post-op office follow up. No chemo, no stage designation, nothing - zero cancer found at the site of the questionable biopsy site.

It’s true the Luxturna is an odd case (though the OP article is talking about customized treatment so it is appropriate here). It’s not the disease or cure but the justification of how they determined the cost of their treatment. Not based on the research cost or market, not based on the production or application of the treatment, but on the value of your eyesight they would be preserving.

Nearly all of the basic research is already taxpayer funded through research grants. There are still development costs (especially trials and such), but most of the money spent my large pharmaceutical companies goes into marketing. (it’s been a few years, but last time I looked in the mid-teens it was more than 50% of their overall budget iirc)

No it will be more expensive. The pricing would be based on how much it currently costs, priced competitively (95% of, say, $500,000) and then they’d add $500,000 to account for the fact that you would recover more of your life and avoid suffering, so $950k total. Of course they may simply price is based on the value of your life. Say the average value of a human is $1.5M in a typical wrongful death suit; they might price it at $1.25M - a bargain!.

Before you laugh at my logic, I’ll point out that Luxturna priced their retinal degeneration drug based on how much value courts placed on lost eyesight. They found that to be around the million-dollar range. The price of treatment was then set at $850,000, because that’s clearly providing value over the monetary equivalent of loss of eyesight (Jeffrey Marrazzo, CEO, was quoted in an interview that this was the basis). Of course, there’s an evilly fun MBA discussion to be had, as well, as your pricing could also be how much it’s worth to a parent not to have to watch their children slowly and unavoidably go blind as they become teenagers. Other drugs are often based on the cost avoidance or value of human life of 100-150k per year, and I’m sure they will argue that a cure should account for the entire life amortization of such a cost. Maybe it will be $5M for someone in their 20s, but only $500k for someone in their 70s.

Which is why the Moderna vaccine will be priced at just 95% of the cost of the repeat treatments and hospitalization plus the value of the time saved and pain and suffering avoidance by the patient. Say, an extra half a million. I mean, what price would you put on avoiding seeing your parent or child subjected to round after round of chemotherapy?

Back in my day there were just two orientations. All these variations are…unnatural. Your screen came out of the box in landscape or portrait, and I don’t believe in any of this “diagonal” nonsense.

Epic doesn’t play nice with Linux, and lemmy is a Linux-centric place - that’s nearly all of the hate. I find Linux to be a pain in the ass because everything else I use, and am of my games, are Windiws native. I click the install button and never have to worry about which version of proton will work. It’s the second worst thing about my Steamdeck (the first is, of course, that atrocious keyboard).

You will be able to tell how rabid the Linux continent is here by the number of down votes I get for saying that windows is simply a better gaming platform and Epics nose-thumbing at Linux causes me exactly zero worries because I play on the OS these games were made for.